Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer

1.Chaffer, C. L. & Weinberg, R. A. A perspective on cancer cell metastasis. Science 331, 1559–1564 (2011).CAS  PubMed  Article  PubMed Central  Google Scholar  2.Tseng, P.-L. et al. The decrease of glycolytic enzyme hexokinase 1 accelerates tumor malignancy via deregulating energy metabolism but sensitizes cancer cells to 2-deoxyglucose inhibition. Oncotarget 9, 18949–18969 (2018).PubMed  PubMed Central  Article  [...]

Published September 17, 2021 at 07:24PM. Read full article at Stem Cells in the News Portal.