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Is It Possible to Regrow Cartilage in the Joints?

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In adulthood, cartilage has almost no regenerative potential. Cartilage damaged by disease, injury, or simply as part of the aging process can therefore not be replaced by the body on its own. As a result, bones may eventually rub against one another, resulting in pain and arthritis, a condition at least a fifth of all [...] Published May 17, 2021 at 08:28AM. Read full article at Stem Cells in the News Portal .

Luspatercept restores SDF-1-mediated hematopoietic support by MDS-derived mesenchymal stromal cells

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Luspatercept/RAP-536 modulates Smad2/3 signaling and Smad4 expression in MSCsStandardized conditions for the in vitro treatment of human MSCs with GDF-11 and the luspatercept homolog RAP-536 were established on the basis of Smad2/3 phosphorylation levels. Recombinant GDF-11 at a concentration of 0.1 µg/ml was found to induce Smad2/3 signaling in both healthy and MDS MSCs, while a [...] Published May 16, 2021 at 07:49PM. Read full article at Stem Cells in the News Portal .

Asia’s Scientific Trailblazers: Sham Mai Har

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Sham Mai HarPro-Vice-ChancellorThe Chinese University of Hong Kong (CUHK)Hong Kong SARAsianScientist (May. 17, 2021) – Before becoming neurons in the brain or immune cells in the blood, all of the human body’s specialized cells trace their origins to stem cells. As if standing at a crossroads, these cells have the near-limitless potential to develop into [...] Published May 17, 2021 at 10:23AM. Read full article at Stem Cells in the News Portal .

Therapeutic implications of transplanted-cell death

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1.Martin, I., Galipeau, J., Kessler, C., Blanc, K. L. & Dazzi, F. Sci. Transl. Med. 11, eaat2189 (2019).CAS  PubMed  Google Scholar  2.Galipeau, J. & Sensébé, L. Cell Stem Cell 22, 824–833 (2018).CAS  PubMed  PubMed Central  Google Scholar  3.Bianco, P. et al. Nat. Med. 19, 35–42 (2013).CAS  PubMed  PubMed Central  Google Scholar  4.Fibbe, W. E., Dazzi, [...] Published May 16, 2021 at 07:58PM. Read full article at Stem Cells in the News Portal .

Frozen Shoulder Manipulation Success Rate: What to Expect

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Shoulder injuries can be debilitating, and a very painful and limiting one is called frozen shoulder. What is a frozen shoulder?  What is frozen shoulder manipulation?  What is the frozen shoulder manipulation success rate?  What should I expect after shoulder manipulation?  What is the best treatment for frozen shoulder?  Let’s dig in. What is a [...] Published May 17, 2021 at 01:01AM. Read full article at Stem Cells in the News Portal .

Is this the End of the Chiro “Stem Cell” Clinic Business Plan?

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One of the hardest things to watch in the stem cell wild west has been chiropractic clinics pretend that they have any idea of which end is up when it comes to delivering orthobiologics. In fact, as I’ve spoken to various chiropractic boards and chiros around the country, it turns out that most boards don’t [...] Published May 16, 2021 at 10:05AM. Read full article at Stem Cells in the News Portal .

How Likely Is a Second ACL Tear On the Same Knee?

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Anterior Cruciate Ligament Injuries and Treatments The ACL (anterior cruciate ligament) is an important knee stabilizing ligament. It prevents the tibia from moving too much frontward (anterior translation) and twisting too much (internal rotation).  It is under most stress with landing from a jump, or a planted foot with twisting, and this is how it [...] Published May 14, 2021 at 11:55PM. Read full article at Stem Cells in the News Portal .