Stem Cells in the News

Bone injuries in the face and skull -- known as craniomaxillofacial defects -- can be caused by sports injuries, vehicle accidents, or battlefield injuries. Repairing such defects is complicated because different types of cells need to interact with each other. In a new study, researchers are investigating the types of material used in reconstruction to [...] Published September 13, 2021 at 09:44PM. Read full article at Stem Cells in the News Portal .

As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity. Researchers from the Max Planck Institute for Biology of Ageing and CECAD [...] Published September 14, 2021 at 12:37PM. Read full article at Stem Cells in the News Portal .

A University at Buffalo-led research team has shown that a protein named for the mythical land of youth in Irish folklore is effective at reversing aging in skeletal muscle cells. Published Sept. 3 in Science Advances, the study centers on the protein NANOG, which is derived from Tír na nÓg, a place in Irish lore [...] Published September 14, 2021 at 06:13PM. Read full article at Stem Cells in the News Portal .

An immunological molecule called fractalkine can boost the production of brain cells that produce myelin, a key factor in diseases such as multiple sclerosis, according to recent research from the University of Alberta. Myelin is an insulating layer around nerves that is gradually worn away by inflammation in multiple sclerosis and similar diseases. Without this [...] Published September 09, 2021 at 01:26PM. Read full article at Stem Cells in the News Portal .

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend on donors for both of these cells. However, a new study led by ASHBi researchers shows that mouse pluripotent stem cells can differentiate into functional [...] Published September 07, 2021 at 10:51AM. Read full article at Stem Cells in the News Portal .

In a new study by Yale Cancer Center, researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters. Targeting these T cells, which are a type of white blood cells, with immunotherapy drugs could increase the number of cancer patients that respond to treatment. The findings were reported online today in [...] Published September 03, 2021 at 09:39AM. Read full article at Stem Cells in the News Portal .

In the United States, as many as 187,000 people are coping with myelodysplastic syndromes (MDS) that damage the bone marrow's ability to produce healthy blood cells. In most cases, MDS is caused by mutations that arise in blood stem cells during a person's life. These patients experience anemia, fatigue, and other complications, with a typical [...] Published September 02, 2021 at 11:52AM. Read full article at Stem Cells in the News Portal .

A study led by researchers from Brigham and Women's Hospital has established a new resource for exploring and understanding Alzheimer's disease (AD) on an individualized level. The team generated induced pluripotent stem cell (iPSC) lines from over 50 different individuals for whom longitudinal clinical data, quantitative neuropathology data, and rich genetic and molecular profiling of [...] Published September 01, 2021 at 11:14AM. Read full article at Stem Cells in the News Portal .

McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy. Due to its resistance to therapy, glioblastoma is the most common and aggressive cancerous brain tumour in adults. It grows fast and spreads quickly. [...] Published August 31, 2021 at 12:42PM. Read full article at Stem Cells in the News Portal .

The human body can be genetically inclined to attack its own cells, destroying the beta cells in the pancreas that make insulin, which helps convert sugar into energy. Called Type 1 diabetes, this disorder can occur at any age and can be fatal if not carefully managed with insulin shots or an insulin pump to [...] Published August 26, 2021 at 04:29PM. Read full article at Stem Cells in the News Portal .

Investigators who previously developed a recipe for turning skin cells into primitive muscle-like cells that can be maintained indefinitely in the lab without losing the potential to become mature muscle have now uncovered how this recipe works and what molecular changes it triggers within cells. The research, which was led by scientists at Massachusetts General [...] Published August 19, 2021 at 07:05PM. Read full article at Stem Cells in the News Portal .

Contrary to the popular song, the neck bone is actually connected to one of 22 separate head bones that make up the human skull. These plate-like bones intersect at specialized joints called sutures, which normally allow the skull to expand as the brain grows but are absent in children with a birth defect called craniosynostosis. [...] Published August 11, 2021 at 11:12AM. Read full article at Stem Cells in the News Portal .

Cambridge scientists have grown beating heart cells in the lab and shown how they are vulnerable to SARS-CoV-2 infection. In a study published in Communications Biology, they used this system to show that an experimental peptide drug called DX600 can prevent the virus entering the heart cells. The heart is one the major organs damaged [...] Published August 05, 2021 at 01:49PM. Read full article at Stem Cells in the News Portal .

Princess Margaret Cancer Centre researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers. The team has made the discovery by performing a deep mechanistic study of lysosomes, which are membrane-bound organelles found in [...] Published August 03, 2021 at 10:06AM. Read full article at Stem Cells in the News Portal .

Drugs must be safe not just for the patients; in the case of pregnant patients, drugs must also be safe for the unborn children still in the womb. Therefore, at an early stage in the development of new medicines, candidate substances are tested in the Petri dish on embryonic stem cells from mouse cell lines. [...] Published July 21, 2021 at 11:24AM. Read full article at Stem Cells in the News Portal .

The sensory cells in the inner ear and the touch receptors in the skin actually have a lot in common, according to a new study from the USC Stem Cell laboratory of Neil Segil published in the Proceedings of the National Academy of Sciences (PNAS). "There are striking similarities in the development of two types [...] Published July 12, 2021 at 02:43PM. Read full article at Stem Cells in the News Portal .

Heart attack, or myocardial infarction, is one of the leading causes of death worldwide. Although modern surgical techniques, diagnostics and medications have greatly improved early survival from these events, many patients struggle with the long-term effects of permanently damaged tissue, and the 5-year mortality rate remains high. Now, researchers reporting in ACS Nano have developed [...] Published July 14, 2021 at 12:36PM. Read full article at Stem Cells in the News Portal .

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients. However, the cell-damaging effect of chemotherapy affects cancer cells but also in principle many other cell types, including cycling blood cells. This puts the [...] Published July 12, 2021 at 12:20PM. Read full article at Stem Cells in the News Portal .

Researchers at the Francis Crick Institute have found a vital mechanism, previously thought to have disappeared as mammals evolved, that helps protect mammalian stem cells from RNA viruses such as SARS-CoV-2 and Zika virus. The scientists suggest this could one day be exploited in the development of new antiviral treatments. On infecting a host, a [...] Published July 08, 2021 at 02:34PM. Read full article at Stem Cells in the News Portal .

A research collaboration based in Kumamoto University, Japan has discovered that muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body. This positional memory was found to be based on the expression pattern of the homeobox (Hox) gene cluster, which is responsible for shaping the [...] Published July 06, 2021 at 11:20AM. Read full article at Stem Cells in the News Portal .