Stem Cells in the News

Newswise — Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection. Their study was published in Nature Communications on 17 September and highlights the usefulness of organoids for [...] Published September 17, 2021 at 02:56PM. Read full article at Stem Cells in the News Portal .

Newswise — ITHACA, N.Y. -- A new Cornell study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.Treating wounds with the secretion of a type of stem cell effectively reduced the viability of methicillin-resistant Staphylococcus aureus – better known as MRSA – according to [...] Published September 16, 2021 at 12:36PM. Read full article at Stem Cells in the News Portal .

Newswise — A textile-based implant containing cartilage derived from stem cells reduced pain and restored hip joint function to baseline levels in a study of dogs with symptoms of moderate osteoarthritis. The study, led by researchers at North Carolina State University, Washington University in St. Louis and Cytex Therapeutics Inc., could be a significant first [...] Published September 15, 2021 at 04:04PM. Read full article at Stem Cells in the News Portal .

Article title: Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulationAuthors: Sarah Elizabeth Blutt, Sue Crawford, Carolyn Bomidi, Xi-Lei Zeng, James Broughman, Matthew Robertson, Cristian Coarfa, Mary Elizabeth Tessier, Tor C. Savidge, F. Blaine Hollinger, Steven Curley, Mark Donowitz, Mary K. EstesFrom the authors: “Here we demonstrate that physical coupling of ex [...] Published September 02, 2021 at 04:04AM. Read full article at Stem Cells in the News Portal .

access_time This news release is embargoed until 25-Aug-2021 at 8:00 PM EDT This news release is available only to verified logged-in journalists until the embargo expires on 8/25/2021 8:00:00 PM. Professional journalists may apply for a PressPass to access embargoed stories. Read original article here. Published August 25, 2021 at 09:36AM. Read full article at Stem Cells in the News Portal .

Newswise — The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death. After an initial [...] Published August 24, 2021 at 07:01AM. Read full article at Stem Cells in the News Portal .

Newswise — An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.The new bioengineered lung model – coined a “clinical [...] Published August 17, 2021 at 02:24PM. Read full article at Stem Cells in the News Portal .

Panelists will discuss breakthrough cases and the possible need for booster shots, as well as their recent research on strength of post-COVID immunity and effectiveness of masks and social distancingMedia Register HereRecent reports suggest that current COVID vaccines may be less effective against the delta variant than earlier studies predicted. The FDA announced emergency use authorization [...] Published August 16, 2021 at 03:27PM. Read full article at Stem Cells in the News Portal .

Newswise — Hematopoietic stem cells — the precursors to blood cells — have been notoriously difficult to grow in a dish, a critical tool in basic research. Scientists at University of California San Diego School of Medicine have identified the underlying issue and developed a method to keep cultured cells healthy. These findings, they say, [...] Published August 12, 2021 at 11:45AM. Read full article at Stem Cells in the News Portal .

Newswise — Its powers may not rival Wolverine’s, but a regenerative implant engineered by researchers at the University of Nebraska Medical Center and University of Nebraska–Lincoln could help repair bone-deep damage following physical trauma, surgery or osteoporosis. The team has developed a biodegradable, nanofiber-based implant, or scaffold, whose design could better regenerate bone by effectively guiding [...] Published August 03, 2021 at 09:54AM. Read full article at Stem Cells in the News Portal .

Newswise — Princess Margaret Cancer Centre researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers.The team has made the discovery by performing a deep mechanistic study of lysosomes, which are membrane-bound organelles found [...] Published August 02, 2021 at 11:47AM. Read full article at Stem Cells in the News Portal .

Newswise — SEATTLE — July 28, 2021 — Researchers at Fred Hutchinson Cancer Research Center published findings in the journal JAMA Network Open indicating that many cancer patients lack sufficient immune protection against the measles and mumps viruses. The highest risk groups within the study were young adults and bone marrow transplant recipients, providing information [...] Published July 28, 2021 at 01:00PM. Read full article at Stem Cells in the News Portal .

Newswise — As the fertilized egg divides, initially undifferentiated cells take on specific functions, becoming more distinct as different tissues and organs emerge. Understanding how hundreds of disparate cell types arise has proven difficult, largely because scientists have lacked the technologies to capture cellular decision making over time.Recent advances have allowed researchers to measure changes [...] Published July 28, 2021 at 02:29PM. Read full article at Stem Cells in the News Portal .

Newswise — Stem cell research holds great potential for regenerative therapies and treatments to combat cardiovascular disease, which is responsible for over 30% of all deaths worldwide.Highly functional cardiomyocytes—the muscle cells responsible for the contraction of the heart—are important for disease modeling, drug screening, and other regenerative medicine approaches.However, the process of differentiating stem cells [...] Published July 28, 2021 at 05:13AM. Read full article at Stem Cells in the News Portal .

Newswise — WASHINGTON, July 27, 2021 -- Cardiovascular diseases account for 32% of global deaths. Myocardial infarction, or heart attacks, play a large part in heart diseases and the necrosis of cardiac tissue after blood supply is decreased or stopped.In APL Bioengineering, by AIP Publishing, researchers from Pohang University of Science and Technology in South [...] Published July 27, 2021 at 11:08AM. Read full article at Stem Cells in the News Portal .

杰克逊维尔市，佛罗里达州 — 妙佑医疗国际正在尝试将再生医学作为多年来的医学难题——椎间盘退行性疾病的一种潜在长期解决方案。世界上有数百万人长期受到由于脊柱经年磨损导致的颈部和背部疼痛的困扰。对于这种常见病痛，目前的治疗通常只能提供暂时的缓解，找到治愈方法是摆在医学研究者面前的一项挑战。Wenchun Qu博士（医学博士）是妙佑医疗国际佛罗里达州杰克逊维尔院区的理疗医生和疼痛专科医生，同时也是妙佑医疗国际再生医学中心再生疼痛医学主任，他提出了一种假设：椎间盘退行性疾病的治疗方案可能就隐藏在间充质干细胞中。这些成体干细胞已经过深入研究证实对人体是安全的。“我在临床前模型中的研究表明，间充质干细胞对于治疗动物椎间盘退行性病况非常有效。我们已进一步与行业赞助者合作，在大型三期临床试验中对间充质干细胞进行测试，目前我们正在等待结果的公布，”Qu博士说。“现在我们正在开发下一代间充质干细胞，它们在治疗椎间盘退行性疾病方面显示出了更加强效的潜力。”妙佑医疗国际再生医学中心为这项研究提供了大力支持，帮助研究团队将这种新型再生生物治疗方法发展成医学实践，从而为需求无法得到满足的患者提供新的治疗选择。Connor Group儿童和社区合作伙伴部也为Qu博士的研究提供了大力支持。脊柱椎间盘是由胶原和蛋白质构成的类似橡胶的柔软垫片，其作用是在脊椎骨之间提供缓冲。它们是保持脊柱灵活性的基础。随着人们年龄的增长，椎间盘可能会破裂，从而导致发炎，使水分子减少。水分的减少进一步导致情况恶化，随着时间的推移，可能会使椎间盘塌陷。椎间盘退行性疾病患者可能出现的典型症状包括刺痛、僵硬和行动问题。这可能会导致一些生活质量问题，例如失去工作、功能下降及活动受限，有时甚至会影响到整个家庭。由于脊柱椎间盘没有血液供应，因此无法治愈或再生。许多治疗试图减轻脊柱恶化的疼痛症状，包括通过椎间盘内注射控制发炎，以及通过电热疗法发送电脉冲震动来麻痹携带疼痛信号的神经。“根据长期研究，患者随访数据已表明这些治疗的效果并不比安慰剂更好，因此几乎已经弃之不用，”Qu博士说。在其他治疗方案都无效的情况下，患者通常会选择手术来融合椎间盘已失效的脊椎骨。然而，脊柱融合术可能无法实现长期的疼痛缓解。Qu博士的假设是间充质干细胞可为减少发炎、缓解疼痛以及恢复脊柱椎间盘提供一种新的选择。他正在将其研究应用到再生医学服务上，这项服务他早在...

Newswise — JACKSONVILLE, Florida: Mayo Clinic estudia la medicina regenerativa como una posible solución a largo plazo para la enfermedad degenerativa de los discos, que ha evadido a la ciencia médica durante años. En todo el mundo, millones de personas sufren dolor crónico del cuello y la espalda, el cual suele aparecer debido al desgaste [...] Published July 22, 2021 at 05:16PM. Read full article at Stem Cells in the News Portal .

Newswise — JACKSONVILLE, Flórida - A Mayo Clinic está buscando a medicina regenerativa como uma solução em potencial a longo prazo para a doença degenerativa do disco que, há anos, não é contemplada pela ciência médica. Milhões de pessoas ao redor do mundo são afetadas por dores crônicas no pescoço e nas costas causadas por anos de desgaste [...] Published July 22, 2021 at 05:32PM. Read full article at Stem Cells in the News Portal .

جاكسونفيل، فلوريدا— تنظر مايو كلينك إلى الطب التجديدي باعتباره حلًا محتملًا طويل الأمد لمرض القرص التنكسي الذي استعصى على علوم الطب لسنوات. يعاني ملايين الأشخاص حول العالم من آلام مزمنة في الظهر والرقبة والتي غالبًا ما تأتي بعد سنوات من التآكل والتلف في العمود الفقري، حيث توفر العلاجات الحالية راحة مؤقتة فقط لهذا الاضطراب الشائع، [...] Published July 22, 2021 at 06:19PM. Read full article at Stem Cells in the News Portal .

Spermatogonial stem cells (SSCs) are essential for male fertility. Using a technique they developed called iSLAMseq, UC San Diego School of Medicine researchers identified waves of genes responding to a transcription factor that promotes SSC formation. This led the group to define a RHOX10-DMRT1-ZBTB16 transcription factor circuit that drives SSC genesis. The finding is another [...] Published July 20, 2021 at 01:44PM. Read full article at Stem Cells in the News Portal .